Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Correlation between change in taste and Danba content during processing of Radix Aconiti lateralis praeparata

Lian Zhong¹, Yun-Wei Wang², Yu-Jie Liu³, Chun-Jie Wu¹, Qin-Wan Huang¹

¹School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137; ²Fuling Hospital of Chinese Medicine, Chongqing 408000; ³School of Pharmacy, Chengdu Medical College, Chengdu 610083, PR China.

For correspondence:- Qin-Wan Huang Email: Huangqinwan@cdutcm.edu.cn Tel:+862861801001

Accepted: 28 July 2019 Published: 29 August 2019

Citation: Zhong L, Wang Y, Liu Y, Wu C, Huang Q. Correlation between change in taste and Danba content during processing of Radix Aconiti lateralis praeparata. Trop J Pharm Res 2019; 18(8):1719-1725 doi: 10.4314/tjpr.v18i8.22

© 2019 The authors.
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Abstract

Purpose: To investigate the correlation between changes in taste and danba content during processing of Radix Aconiti lateralis praeparata (RALP).

Methods: Danba content was determined by Na2EDTA titration method, while electronic tongue technique was used to determine variations in taste during processing of RALP. Principal components analysis (PCA) and discriminant factorial analysis (DFA) were used for analysis of data on taste variation. The correlation between danba levels and changes in taste was determined using Pearson correlation test.

Results: The results showed that danba content increased sharply after fresh RALP was soaked in danba solution, and then decreased with each step in the processing of RALP. Electronic tongue successfully distinguished among the different processed RALP samples and identified unknown samples through PCA and DFA. Pearson correlation analysis showed that danba content was negatively correlated with taste.

Conclusion: Taste variation is closely correlated with danba content during the processing of RALP. Moreover, electronic tongue is a suitable supplementary tool for the quality control of RALP.

Keywords: Radix Aconiti lateralis praeparata, Fuzi, Danba, Taste variation, Electronic tongue